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Aleemuddin, N. M.
- Acute Neurotoxicity with Appropriate Dose of Isoniazid: a Case Report
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Authors
Affiliations
1 Rajiv Gandhi Institute of Medical Sciences Adilabad 504001, A.P, IN
1 Rajiv Gandhi Institute of Medical Sciences Adilabad 504001, A.P, IN
Source
Indian Journal of Public Health Research & Development, Vol 2, No 1 (2011), Pagination: 133-134Abstract
Isoniazid (INH) is most frequently used in combination with other drugs for the treatment of tuberculosis or as monotherapy for treatment of latent tuberculous infection. Seizures due to anti-tubercular chemotherapy are a rare side effect. INH causing status epilepticus has been very rarely reported to cause seizures. We present a patient who, after 5 months of treatment with appropriate dose of INH, evolved to status epilepticus. Seizures could be controlled only after administering of pyridoxine.Keywords
Isoniazid, Acute Neurotoxicity, Status Epilepticus, Seizures, Pyridoxine
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